European Joint Programme on Rare Diseases (EJP RD) Call for Proposals 2020 "PRE-CLINICAL RESEARCH TO DEVELOP EFFECTIVE THERAPIES FOR RARE DISEASES"
13-01-2020
The ERA-Net E-Rare has successfully implemented ten Joint Transnational Calls for rare disease research projects since 2006. This effort continues in the framework of the European Joint Programme on Rare Diseases (EJP RD) that has been established to further help in coordinating the research efforts of European, Associated and non-European countries in the field of rare diseases and implement the objectives of the International Rare Disease Research Consortium (IRDiRC).
A number of national and regional funding organisations will participate in the EJP RD Joint Transnational Call (JTC) 2020 and will fund multilateral research projects on rare diseases together with the European Commission (EC) under the EJP-COFUND action.
The aim of the call is to enable scientists in different countries to build an effective collaboration on a common interdisciplinary research project based on complementarities and sharing of expertise, with a clear future benefit for patients.
Research proposals must cover at least one of the following areas:
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Development of novel therapies in a preclinical setting (including small molecules, repurposing drugs, cell and gene advanced therapies) focusing on condition(s) with unmet medical needs
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Use of disease models suitable for medicinal product’s development according to EMA guidelines
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Development of predictive and pharmacodynamics (PD) biomarkers (with appropriate analytical methods e.g. OMICS) in a preclinical setting (e.g. in the validated model or in pre-collected human samples) for monitoring the efficiency of the therapy. The model chosen must mimic the human diseases and be transposable so that the biomarker identified in animals can be valid for humans
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Proof of principle studies fostering an early (pre-clinical) stage of drug development (excluding interventional clinical trials of phase 1-4).
Greek entities participating in consortia submitting successful proposal are to be funded by the General Secretariat for Research and Technology (GSRT) under the Operational Programme “Competitiveness, Entrepreneurship and Innovation” (EPAnEk) 2014-2020. The GSRT contribution to this Call will amount to 800,000.00 €. The above Greek contribution will be distributed to recipients as follows: up to 200,000.00 € per proposal with a Greek partner; and up to 250,000.00 € per proposal with a Greek coordinator, according to the specific national conditions for the Action, as described in the relevant Annex of the Joint Call Guidelines for Applicants.
The maximum duration of the project is three years.
Only transnational projects will be funded. Each
consortium submitting a proposal must involve four to six eligible principal investigator partners. No more than two eligible partners from the
same country can be present in each consortium (further national limits may
apply). This limit applies to Early Career Researchers and partners from
underrepresented countries (see below). PAOs requesting funding do not count
toward this total.
consortium submitting a proposal must involve four to six eligible principal investigator partners. No more than two eligible partners from the
same country can be present in each consortium (further national limits may
apply). This limit applies to Early Career Researchers and partners from
underrepresented countries (see below). PAOs requesting funding do not count
toward this total.
The number of partners can be increased to 8 in two cases:
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The inclusion of partners from participating countries usually underrepresented in projects (Czech Republic, Slovakia, Hungary, Lithuania, Poland, and Turkey).
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The inclusion of Early Career Researchers as full partners.
There will be a two-stage submission procedure for joint applications: pre-proposals and full proposals.
Registration deadline : 18th February 2020.
Pre-proposal submission deadline: 18th February 2020.
Invitation to full proposal: end April 2020.
Full proposal submission deadline: 16th June 2020.
Deadline for rebuttals: 28th July 2020.
Notification of funding decision: November 2020.
For further information, please consult the following link::